Avoid Routine Proton Pump Inhibitor Therapy for Prophylaxis in Hospitalized Patients Preface: A retrospective study at a Boston hospital examined the effect of routine proton pump inhibitor therapy in hospitalized stroke patients. No clear benefit was seen and multivariate analysis…
Read MoreMore Articles – Emergency Procedures, Glidescope Intubation, medical procedures, Respiratory diseases
Preface: This retrospective study examined physician performed prehospital intubations between 2008 and 2012 in Scottish aeromedical transport system. Over 200 intubations were analyzed and 75% of the intubations were during inter facility transport and 25% at the scene. There was…
Read MoreNo role for routine carotid doppler ultrasounds to screen for carotid artery stenosis prior to noncardiac surgery Preface: Carotid artery doppler ultrasound scans are frequently ordered prior to noncardiac surgery to decrease the chance of a perioperative stroke. The assumption…
Read MoreSteroids beneficial in refractory septic shock Preface: This multi-center observational study of over 1,800 patients examined whether low-dose steroids (<80 mg prednisone equivalents) was superior to placebo for patients in septic shock. There results showed that there was a slight…
Read MoreThe new direct target-specific oral anticoagulants (TSOACs; dabigatran, rivaroxaban, apixaban, and edoxaban) have been compared with vitamin K antagonists (VKAs; warfarin and similar agents) for acute venous thromboembolism (VTE) in six recent phase III clinical trials encompassing more than 27,000…
Read MoreIn a recent retrospective study from Mayo Clinic, researchers demonstrated that intravenous contrast material was not associated with acute kidney injury (i.e., increase in serum creatinine level of ≥0.5 mg/dL) during the 72 hours after computed tomography (CT) of the…
Read MoreAdvise patients to drink at least 2 L daily; consider thiazide diuretics, citrate therapy and allopurinol for patients with “active” calcium stone formation. American College of Physicians (ACP) Key Recommendations Increased fluid intake to achieve 2 L of urine output daily…
Read MoreIn a new meta-analysis, early management of non–ST-segment elevation myocardial infarctions with thienopyridines was not associated with significantly lower mortality and did not lower major adverse cardiovascular event rates for those eventually undergoing PCI. Current ACC/AHA guidelines support dual antiplatelet…
Read MoreThe American Heart Association/American Stroke Association has updated its comprehensive acute ischemic stroke care guidelines in 2013. The following is a summary of the most important new recommendations: Teleradiology networks are recommended for community hospitals that lack access to neurological…
Read MoreCardiac arrest patients who were intubated had similar outcomes to those who had a supraglottic airway device (e.g., King tube) inserted in the pre-hospital setting. A literature review of 5 studies and over 300,000 patients with pre-hospital cardiac arrest demonstrated…
Read MoreTranexamic acid is a simple little molecule, just a synthetic derivative of the amino acid lysine. But it’s also a potent pro-hemostatic drug that binds plasminogen and plasmin and stops the degradation of fibrin (the stuff in blood clots). Now…
Read MoreCompared with warfarin, the new agents significantly reduced all-cause and vascular mortality. The new direct-acting oral anticoagulants (DOACs; dabigatran, rivaroxaban, apixaban, and edoxaban) have been found to be noninferior to vitamin K antagonists in clinical trials of stroke prevention in…
Read MoreAmong the 53% of patients with negative bronchoalveolar lavage results, alternative explanations for fever and for pulmonary infiltrates were established in 61% and 46%, respectively. Chest x-ray abnormalities, leukocytosis, purulent tracheal aspirate, or fever in a mechanically ventilated patient raise…
Read MoreA recent study concluded that assessing the ability of patients to list the months of the year backwards in addition to an assessment of subjective confusion and disorientation was accurate at diagnosing delirium in hospitalized adult patients. The months of…
Read MoreA new randomized controlled trial out of the UK that investigated 540 patients with ARDS from sepsis showed no benefit of statins. The study investigated the use of Simvastatin 80 mg/day vs placebo in patients with ARDS from sepsis and…
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