Xigris – Hospital Procedures Consultants

The Rise and Fall of Xigris (Drotrecogin-alfa)

October 31, 2011

More Articles – Sepsis, Septic Shock, Xigris

Drotrecogin-alfa (DrotAA) has been an integral part of the care bundle for adult patientshospitalized with severe sepsis or septic shock and a high risk of death since 2002. DrotAA is a synthetic activated Protein C (APC) which has good scientific…

2017 (1)
abdominal aortic aneurysm (1)
Abusive head trauma (1)
ACLS (3)
Acute Appendicitis (1)
Acute Bacterial Meningitis (1)
Acute Coronary Syndrome (3)
acute glomerulonephritis (1)
acute interstitial nephritis (1)
acute kidney injury (5)
acute myocardial infarction (1)
Acute pancreatitis (1)
Acute respiratory distress syndrome (1)
acute tubular necrosis (1)
advanced airway (1)
AHT (1)
Airway management (8)
alcoholic hepatitis (1)
Alcoholic liver disease (2)
Allen's Test (1)
Amiodarone (1)
Anemone (1)
Anti-coagulant (1)
antibiotic stewardship (2)
antibiotics (2)
Anticoagulants and Procedures (1)
Anticoagulation (6)
antimicrobial stewardship (1)
Antiplatelet therapy (1)
antiplatelets (2)
antiretroviral therapy (1)
antiviral (1)
Aortic dissection (1)
aortic stenosis (1)
Appendectomy (1)
Aquariums (1)
Architecture (1)
ARDS (7)
Arterial Line (1)
Arterial line insertion (1)
Arterial line placement (3)
Arterial line-associated bloodstream infections (1)
Arterial Lines (5)
ascites (2)
Aspirin and Cancer Risk (1)
asystole (1)
ATN (1)
Atraumatic spinal needles (1)
atrial fibrillation (5)
atrial flutter (1)
Austin (1)
automated external defibrillators (1)
AV block (1)
awake intubation (1)
back pain (1)
bacteremia (3)
bacterial meningitis (1)
Bellagio (1)
Beta-blockers and COPD (1)
beta-lactam antibiotics (2)
Bilevel noninvasive positive pressure ventilation (1)
BiPAP (3)
BLOG OF THE WEEK (1)
bloodstream infections (1)
blunt trauma (1)
BNP (1)
Booty (1)
Boston Procedures Course (2)
Bova score (1)
Brain injury (1)
C-MAC D-blade (1)
C-spine clearance (1)
CABG (1)
Cancer (3)
candidiasis (1)
CAP (1)
Cardiac Arrest (8)
cardiac arrest survival (1)
Cardiac ischemia (1)
cardiac monitoring (1)
cardiac syncope (1)
Cardiac tamponade (1)
cardiovascular events (1)
Carotid Artery Stenosis (1)
Catheter (1)
Catheter-associated UTI (1)
catheter-directed thrombolysis (1)
Catheter-related bloodstream infections (2)
cellulitis (2)
Central Line (7)
central line associated bloodstream infections (2)
central line complications (2)
Central line insertion (2)
central line placement (8)
central lines (8)
Central Venous Catheter (6)
central venous catheters (3)
Central venous pressure (1)
cervical spine injury (1)
CHADS2-VASc score (1)
Chest Pain (3)
Chest tube (7)
chest tube position (1)
Chest tube removal (1)
chest tube size (1)
chest tubes (3)
Chest wall thickness (1)
CHF (1)
Chicago (2)
Chicago Procedures Course (3)
choosing wisely (1)
Chronic Obstructive Pulmonary Disease (1)
Cirrhosis (6)
Cirrhotic ascites (1)
Clopidogrel (1)
coagulopathy (2)
Colorado River (1)
coma (1)
comatose survivors (1)
community-acquired pneumonia (3)
Computed tomography (1)
concussion (1)
Conference (2)
Conservative fluid management (1)
Conservatory at Bellagio (1)
contact dermatitis (1)
COPD (3)
COPD exacerbations (3)
coronary angiography (1)
coronary stent (1)
Coronoary artery bypass (1)
corticosteroids (1)
CPAP (1)
CPR (4)
cricothyroidotomy (1)
critical illness (1)
cryptogenic strokes (1)
CSF Lactate Level (1)
CT pulmonary angiogram (1)
CT Scan (3)
CT scans (2)
CVP (1)
D-dimer (4)
daily lab testing (1)
Deep vein thrombosis (2)
Deep venous thrombosis (4)
Defibrillation (1)
Delirium (2)
Denver Procedures Course (1)
Device-related infections (2)
diabetes (1)
diabetes mellitus (1)
Diagnosis (1)
difficult airway (1)
difficult airway management (2)
Difficult Intubation (1)
Difficult LMA (1)
direct laryngoscopy (4)
diuretics (1)
Diverticulitis (1)
dosage (1)
Drug interactions (1)
DVT (1)
DVTS (1)
dyspnea in ER (1)
E-FAST (2)
ECG (1)
Eddie V's (1)
EEG (1)
electroencephalogram (1)
Emergency Department (1)
emergency department triage (1)
emergency procedures (3)
emergent intubation (1)
Encephalitis (1)
Endotracheal Intubation (17)
Epidemiology (1)
epidural hematoma (2)
epidural steroid injections (1)
Euthanasia (1)
Exacerbations (1)
extubation (1)
FACTT (1)
FACTT Conservative (1)
FACTT Liberal (1)
FACTT Lite (1)
falls (1)
FAST exam (1)
Featured (31)
Featured Procedure (29)
femoral lines (1)
Fentanyl-Based Ventilator (1)
First-attempt success rate (1)
Fluid and Catheter Treatment Trial (1)
fracture reduction (1)
fractures (1)
Frost Bank Tower (1)
GI bleed (1)
GI bleeding (1)
GlideScope (1)
Glidescope Intubation (7)
Goal peripheral oxygen saturation (1)
gout or pseudogout (1)
Guidelines (2)
Guidlelines (3)
HACOR (1)
Handgrip Strength Test (1)
head trauma (2)
Headache (2)
healthcare-associate pneumonia (1)
heart block (1)
Heart failure (2)
hemodynamic monitoring (1)
hepatic encephalopathy (1)
hepatic hydrothorax (1)
hepatitis (1)
hepatorenal syndrome (1)
HIV (1)
hospital procedures (1)
hospital-acquired conditions (1)
Hospitalist (2)
HPC (3)
HPC Blog Updates (2)
HPC Conference (1)
HPC travel blog (1)
HPC update (2)
HPC Updates (189)
hyperglycemia (1)
hyperkalemia (1)
Hypertrophic cardiomyopathy (1)
hypothermia (1)
Hypoxia (1)
ICH (1)
ICU (1)
ICU quality care (1)
ICU quality control (1)
IJ lines (1)
Infants (1)
infection control (1)
influenza (1)
Informed consent (1)
inpatient mortality (1)
Inracranial Hemorrhage (2)
intermediate airways (3)
internal jugular line (1)
intra-abdominal infections (1)
Intracerebral Hemorrhage (1)
intraosseous line (1)
Intubation (19)
IO line (1)
ischemic strokes (2)
IV contrast (1)
Ketofol (1)
kidney stones (1)
King Tube (5)
laceration repair (1)
Laryngeal Mask Airway (5)
Las Vegas (4)
Las Vegas Procedures Course (2)
Lidocaine (1)
LMA (1)
Lumbar Puncture (14)
lung ultrasound (1)
M&M's World (1)
Magnetic resonance imaging (1)
major adverse cardiac events (1)
Major trauma (1)
Management (1)
massive transfusion protocol (1)
Mechanical Ventilation (17)
medical procedures (1)
meningitis (2)
minimally responsive state (1)
Miracle Mile Shops (1)
MRI (1)
MRSA (1)
Music Capital of the World (1)
myocardial infarction (1)
National Institute for Health and Care Excellence (1)
Needle Decompression (1)
Needle decompression catheter (1)
nephrolithiasis (2)
Neuroimaging (1)
New Oral Anticoagulants (1)
New Orleans Procedures Course (1)
NOACs (1)
Nocturnal continuous positive airway pressure (1)
Non–ST-segment elevation myocardial infarction (1)
Nonalcoholic liver disease (2)
noninvasive positive pressure ventilation (1)
noninvasive ventilation (2)
nosocomial infections (1)
NPPV (1)
NSTEMI (3)
Obesity hypoventilation syndrome (1)
Obstructive sleep apnea (1)
OHS (1)
Orlando Procedures Course (1)
OSA (1)
out of hospital cardiac arrest (1)
Oxygenation goals (1)
Palpation-guided placement (1)
Pancreatitis (1)
Paracentesis (7)
parenteral nutrition (1)
PCI (2)
PDPH (1)
PEA (1)
Pediatric Lumbar Puncture (1)
PEEP (1)
percutaneous coronary intervention (2)
perioperative complications (1)
persistent vegetative state (1)
Photos From the Field (1)
Physician-Assisted Suicide (1)
PLAD Score (1)
Planet Hollywood (2)
Plant Hollywood (1)
Plavix (2)
pleural effusions (3)
pleural fluid analysis (1)
Pleural space (1)
pneumonia (8)
Pneumothorax (4)
portal vein thrombosis (1)
Positive end expiratory pressure (1)
post-cardiac arrest care (1)
Post-dural puncture headache (2)
postpartum hemorrhage (1)
Predictive Laryngeal Mask Airway Difficulty Score (1)
preoxygenation (1)
prerenal azotemia (1)
Press (2)
pressure ulcers (1)
procalcitonin (2)
Procalcitonin levels for infections (1)
Procedural Sedation (4)
Procedure Blog of the Week (19)
PROCEDURE OF THE WEEK (1)
procedures (1)
procedures blog of the week (1)
Procedures in Cirrhotic Patients (1)
prone positioning (1)
Prophylaxis (1)
Propofol (1)
Protocolized Sedation (1)
Proton pump inhibitors increase infection risk (1)
Pulmonary artery occlusion pressure (1)
Pulmonary Embolism (9)
pulmonary embolus (1)
pulseless electrical activity (1)
quality care (1)
Radial Artery Catheterization (1)
rapid sequence intubation (3)
RASS (1)
rate control rhythm control (1)
re-expansion pulmonary edema (1)
readmission (2)
readmission rates (1)
Resident work hour restrictions (1)
respiratory failure (2)
respiratory tract infections (1)
return of spontaneous circulation (2)
Richmond Agitation-Sedation Scale (1)
Risk Factors (1)
Risks (1)
ROSC (3)
RUSH Exams (2)
safety checklists (1)
Saftey techniques (1)
San Antonio (1)
San Antonio Procedures Course (1)
San Francisco Procedures Course (2)
SBP (1)
sciatica (1)
screening (1)
Sedation (1)
Sepsis (11)
Septic Shock (6)
Severe prosthetic valve dysfunction (1)
severe sepsis (1)
shock (2)
shock index (1)
Shockable Rhythm (1)
shockable vs. nonshockable rhythms (2)
Simulation Based Training (1)
Simulation-based procedural training (2)
sinusitis (1)
Sixth St. (1)
skin infection (1)
Sleep-disordered breathing (1)
Small-bore chest tube (1)
spinal headache (1)
spinal stenosis (1)
Spine Injury (1)
Spontaneous bacterial peritonitis (2)
Spring (1)
Staph aureus (1)
Statins (2)
steroids (3)
stethoscopes (1)
Street Scene (1)
stroke (4)
subarachnoid hemorrhage (2)
subclavian line (2)
Sudden death (1)
Summer (1)
Sunken treasure (1)
supraglottic airway (1)
supraglottic airways (1)
surgical airway (1)
surgical bleeding (1)
Sushi (1)
Suspected Acute Aortic Syndromes (1)
syncope (4)
Systemic inflammatory response syndrome (1)
Tension pneumothorax (1)
thiazides (1)
Thienopyridines (1)
Thoracentesis (13)
thrombocytopenia (3)
thrombolysis (1)
Thumb Capillary Lactate (1)
Thumb Plethysmography (1)
TN (1)
Tourism (1)
TPA (1)
transexamic acid (1)
transfusion (1)
transfusions (2)
transtracheal ultrasound (1)
Trauma (6)
Trauma CME (1)
traumatic brain injury (1)
traumatic lumbar puncture (1)
Traumatic needles (1)
traumatic shock (1)
Travel (16)
Travel Blog (6)
troponin (1)
Tube Thoracostomy (8)
TXA (1)
Ulnar Frame Count (1)
Ultrasound (4)
Ultrasound for Pneumothorax (1)
ultrasound-guided arterial lines (2)
Ultrasound-Guided Central Line Insertion (2)
Ultrasound-guided lumbar puncture (1)
Ultrasound-Guided Lumbar Punctures (1)
Ultrasound-Guided Paracentesis (1)
Ultrasound-Guided Peripheral IV Insertion (2)
ultrasound-guided procedures (10)
Ultrasound-guided radial artery line placement (1)
Ultrasound-Guided Thoracentesis (3)
Unstable Angina (2)
Updated guidelines (1)
UTI (1)
VAP (1)
Vascular access (2)
vasopressors (3)
venous stasis dermatitis (1)
Venous Thromboembolic Disease (1)
venous thromboembolism (5)
venous thrombosis (1)
Ventilation (1)
ventilation-perfusion lung scan (1)
ventricular fibrillation (2)
ventricular tachycardia (2)
video laryngoscopy (5)
Videolaryngoscopy (1)
VTD (1)
VTE (1)
Wake-up and Breath Protocol (1)
Wells score (1)
Windy City (1)
Xigris (1)
zoster (1)

The Rise and Fall of Xigris (Drotrecogin-alfa)

Categories