There have been multiple strategies to determine the “optimal PEEP” in acute respiratory distress syndrome (ARDS).  One strategy is to perform a recruitment maneuver using an “Open Lung” approach and neuromuscular blockade (with pressures as high as 60 cm H2O),…
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Definitions Presumed source with SIRS criteria = infection Infection with life-threatening organ dysfunction = sepsis Sepsis refractory to intravenous fluid challenge = septic shock Treatment of sepsis or septic shock Draw blood cultures x 2 Analyze any fluid that may…
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A retrospective study compared the performance of Fluid and Catheter Treatment Trial (FACTT) Lite, FACTT Conservative, and FACTT Liberal. The prior FACTT demonstrated that conservative fluids is superior to liberal fluids for ARDS. A simplified conservative fluid protocol (FACTT Lite)…
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Presently, the mortality of patients in the hospital with acute respiratory distress syndrome (ARDS) is higher than 40%.  A sixteen month long observational study was conducted to determine if certain cutoff points of PaO2/FiO2 (less than or equal to 200…
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More Articles – ARDS, HPC Updates, Statins
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A new randomized controlled trial out of the UK that investigated 540 patients with ARDS from sepsis showed no benefit of statins.  The study investigated the use of Simvastatin 80 mg/day vs placebo in patients with ARDS from sepsis and…
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